Symptoms of postural orthostatic tachycardia syndrome in pregnancy: a cross-sectional, community-based survey.

This study investigates the relationship between pregnancy and the symptoms of Postural Orthostatic Tachycardia Syndrome (POTS) through a cross-sectional survey of 8941 females diagnosed with POTS. It found that symptoms often worsen during different stages of pregnancy, particularly in the first and third trimesters, as well as postpartum. Those who experienced symptoms worsening in the first trimester typically continued to worsen throughout pregnancy. In some cases, pregnancy was noted as a trigger for the initial onset of POTS. The findings highlight a potential predictive relationship between early pregnancy symptoms and their progression, offering valuable insights for clinicians counseling pregnant patients with POTS or those considering pregnancy. The study also considers the impact of comorbid conditions such as Ehlers-Danlos syndrome or autoimmune disorders on POTS symptoms during pregnancy.