Sick Sinus Syndrome Can Be Associated with Postural Tachycardia Syndrome and Inappropriate Sinus Tachycardia Syndrome.

This resource discusses the potential relationship between sinus node dysfunction, specifically sick sinus syndrome, and rarer forms of tachyarrhythmia such as postural tachycardia syndrome (POTS) and inappropriate sinus tachycardia. While such crossovers between sinus node dysfunction and common atrial arrhythmias are known in older individuals, this is one of the first documentations of such associations with POTS. The authors explore the possible pathological mechanisms behind these occurrences and propose an initial treatment algorithm for managing sinus node dysfunction in the context of these conditions, based on current evidence.