Recognizing hESD & HSD, Differential Diagnoses | Dr. Andrew Maxwell, MD, Pediatric Cardiology

Dr. Andrew Maxwell's presentation at the EDS Conference focuses on diagnosing hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD). hEDS/HSD are characterized by symptoms such as joint hypermobility, chronic pain, and various comorbidities like POTS and MCAS. The presentation discusses the "PENTAD," linking hEDS/HSD with associated conditions like dysautonomia, digestive issues, allergies, and autoimmune disorders. The current 2017 diagnostic criteria for hEDS are reviewed, with criticisms and proposed updates, particularly for pediatric diagnoses. There's also a strong emphasis on the interconnectedness of these conditions, proposed mechanisms like the "syndrome of sag," and ongoing research needs to refine criteria and treatments. Additionally, studies show strong correlations between POTS, MCAS, and hypermobility disorders, necessitating further research and collaboration among experts to enhance diagnosis and management strategies.