Proceedings from the Inaugural American Initiative in Mast Cell Diseases (AIM) Investigator Conference.

The inaugural AIM investigator conference focused on mast cell diseases, convening to foster a collaborative network among American and European scientists and clinicians specializing in this field. Highlights from the conference include discussions on the biology of mast cells, the genetic basis of hereditary alpha-tryptasemia, and the diverse manifestations and management of mast cell activation syndromes, allergies, and mastocytosis. The meeting underscored the heterogeneity among mast cell disorders and aimed to enhance cooperation in research efforts across continents to better understand these rare conditions and advance diagnostic and therapeutic options.