Postural Tachycardia Syndrome (PoTS)

Dr. Blair Grubb discusses the nature, diagnosis, and treatment of Postural Orthostatic Tachycardia Syndrome (PoTS), emphasizing its status as an abnormal physiological condition rather than a standalone illness. The condition arises when the body fails to maintain vascular resistance, causing blood pooling and compensatory heart rate increase, leading to symptoms such as fatigue, dizziness, and exercise intolerance. Diagnosis is primarily clinical, marked by a significant increase in heart rate upon standing. PoTS often affects adolescents and has a higher prevalence in females. It can be linked to conditions like Ehlers-Danlos Syndrome or triggered by viral infections, with some showing a post-viral autoimmune component. Treatment involves a combination of reconditioning exercises, increased salt and fluid intake, and, if necessary, medication. While many patients improve significantly over time, the condition can be life-altering, necessitating tailored management strategies to maximize quality of life.