Patient's Interview with Dr. Blair P. Grubb on POTS subtype Hyperadrenergic (MCA)

In this interview, Dr. Blair P. Grubb discusses the Hyperadrenergic subtype of Postural Orthostatic Tachycardia Syndrome (POTS) which may involve Mast Cell Activation Syndrome (MCAS) in a teenage patient. The hyperadrenergic form of POTS is characterized by high heart rates and blood pressure, with some cases being associated with mast cell instability, leading to symptoms like flushing and significant dizziness. Diagnosing the subtype can involve clinical assessments and measuring urinary histamine levels, though these are not widely available. Treatments often include antihistamines and H2 blockers. Exercise is emphasized as crucial for managing POTS symptoms. There is ongoing research into the genetic and autoimmune aspects of this condition, although it is a less common form of POTS.