Pain and Hypermobility with Dr. Linda Bluestein as part of the Mast Cell Matters series

In this insightful episode of Mast Cell Matters, Dr. Linda Bluestein, a renowned anesthesiologist and pain specialist, discusses the intersection of MCAS, hypermobility, and pain management with Dr. Tania Dempsey. Dr. Bluestein highlights the connection between mast cell activity and systemic symptoms, emphasizing that many patients with hypermobility disorders, such as EDS, benefit significantly from treatments targeting mast cell stabilization. She uses a comprehensive approach to pain management, including non-opioid pharmacological treatments like ketamine and addressing lifestyle factors through an acronym MENS PMMS. This approach includes movement, education, nutrition, sleep, psychosocial aspects, and various modalities, medications, and supplements. While discussing opioids, Dr. Bluestein warns about certain opiates that trigger mast cell activation and promotes alternatives like ketamine and cannabis, stating their benefits in managing chronic pain and stabilizing mast cells. She also expresses caution about intensive pain programs for adolescents, advocating for a more patient-specific approach to treatment. Overall, the episode provides a thorough examination of the complex interplay between hypermobility disorders, mast cell activation, and chronic pain, offering insights into effective treatment strategies.