Overview of Autonomic Disorders

In his overview of autonomic disorders presented at Dysautonomia International's 2020 Virtual Conference, Dr. Blair Grubb provides a detailed explanation of the autonomic nervous system and conditions such as syncope, POTS, and EDS. Dr. Grubb explains syncope types, such as neurocardiogenic and orthostatic, while detailing the physiological mechanisms involved, like the autonomic nervous system's regulation of heart rate and blood pressure. His talk touches upon the genetic and potential autoimmune components of autonomic disorders, discusses the frequency and symptoms of POTS, and explores the relationship between POTS and EDS, suggesting a potential link with immune dysfunction. He describes the importance of tilt table testing for diagnosis, though not exclusively necessary, and potential treatment options including immune-modulating drugs. He also highlights the implications of individual symptoms, comorbidities, and the importance of a comprehensive approach to patient management.