New Clues in Plasma Proteins in POTS Patients with Dr. Artur Fedorowski

This episode features Dr. Artur Fedorowski discussing his recent research on plasma proteins in POTS patients. Dr. Fedorowski, a leading POTS researcher, explains that his study identified several plasma proteins that are differentially expressed in POTS patients compared to healthy controls. Notably, 18 out of 19 upregulated proteins are linked to blood coagulation, suggesting a hypercoagulable state in these patients. This novel finding highlights potential underlying mechanisms behind POTS, such as increased blood clotting risks, inflammation, and adrenergic activity, which may contribute to symptoms. The episode also addresses Dr. Fedorowski's development of a new POTS symptom score, which highlights the severity and range of symptoms beyond tachycardia, emphasizing the systemic impact of the condition. Dr. Fedorowski stresses the importance of these findings in guiding future research and enhancing understanding of POTS pathophysiology.