New Clues in Plasma Proteins in POTS Patients with Dr. Artur Fedorowski

In this podcast episode, Dr. Artur Fedorowski, a leading researcher in POTS, discusses his recent study on plasma proteins in POTS patients compared to healthy controls. The study revealed that POTS patients have a distinct protein signature indicative of underlying hypercoagulability, inflammation, potential cardiac involvement, and adrenergic hyperactivity. Interestingly, the hypercoagulable state was a particularly strong finding, which raises questions about the role of subtle blood clotting abnormalities in POTS. Dr. Fedorowski highlighted that while these findings provide new insights into the mechanisms of POTS, they also open avenues for further exploration into potential diagnostic tools and treatments. Additionally, he introduced a new POTS symptom score, emphasizing that POTS is not just about tachycardia but involves a wide range of debilitating symptoms. The episode emphasized the complexity and multifaceted nature of POTS, with an encouragement for further research to better understand and treat this condition.