Misbehaving Mast Cells with Dr. Lawrence Afrin

In this podcast episode, Dr. Lawrence Afrin, a leading expert in mast cell research, discusses how mast cell activation syndrome (MCAS) can contribute to the symptoms of postural orthostatic tachycardia syndrome (POTS), including the occurrence of flare-ups. Dr. Afrin explains that misbehaving mast cells, which are part of the body's immune system, may release excessive amounts of chemicals that lead to various symptoms and syndromes like POTS. These insights are grounded in the concept of mast cell activation disease, as detailed in his book "Never Bet Against Occam," which examines the relationship between mast cell dysfunction and chronic illness. The episode provides valuable knowledge for those suffering from POTS or MCAS, as well as for clinicians treating these conditions.