Mast Cell Matters: Diagnosis and Treatment of MCAS with Dr. Tania Dempsey

In this episode, Dr. Tania Dempsey discusses the complexity of diagnosing and treating Mast Cell Activation Syndrome (MCAS). She emphasizes the multisystemic nature of the condition, often misdiagnosed due to overlapping symptoms with other conditions like POTS. Dr. Dempsey outlines diagnostic criteria, including the necessity of multi-system involvement and specific testing methods, such as blood and urine tests for mast cell mediators. Treatment involves identifying and eliminating triggers, using antihistamines, and potentially other medications like sodium cromolyn or montelukast. Non-pharmacological interventions, such as limbic retraining programs, are also highlighted. Dr. Dempsey stresses that managing MCAS requires patience, a methodical approach, and ongoing adjustments as triggers and responses can vary greatly among individuals.