Mast Cell Activation Syndrome with Dr. Tania Dempsey: Rational Wellness Podcast 303

In this episode of the Rational Wellness Podcast, Dr. Tania Dempsey, a leading expert on Mast Cell Activation Syndrome (MCAS), discusses the condition with Dr. Ben Weitz. MCAS involves inappropriate and excessive release of chemical mediators by mast cells, leading to a range of multi-systemic symptoms. Dr. Dempsey outlines diagnostic challenges, noting that it requires complex lab tests and often involves assessing symptoms across multiple organ systems. The interview covers potential genetic predispositions to MCAS, its triggers, and criteria for diagnosis, emphasizing the importance of personalized treatment plans. These plans often start with eliminating triggers and may include antihistamines, mast cell stabilizers, diet alterations, and integrative approaches. She also highlights a frequent association between MCAS and other conditions like allergies, gastrointestinal issues, and autoimmune disorders. Dr. Dempsey advises clinicians to consider MCAS in patients with unexplained multi-systemic symptoms and encourages patients to advocate for comprehensive evaluations.