Mast Cell Activation Symptomatology (Part 2 of 3)

This video, part of a series on mast cell disorders, provides an in-depth look at the symptomatology and diagnostic process related to mastocytosis and related conditions. Key experts such as Drs. Akin, Castells, Theoharides, and Greenberger discuss the World Health Organization's criteria for diagnosis, emphasizing that a definitive diagnosis often requires a bone marrow biopsy to identify abnormal mast cell clusters and genetic mutations. They note that symptoms include skin rashes, gastrointestinal issues, and other systemic effects. The variability and unpredictability of symptoms are highlighted by patient testimonies. Management strategies often involve the prescription of self-injectable epinephrine and medications such as sodium cromolyn to inhibit mast cell mediator release. This resource serves as an informative guide to both the challenges and approaches in managing mast cell activation disorders.