Mast cell activation disorder with Dr. Anne Maitland

In a webinar presented by Dr. Anne Maitland, a comprehensive overview of Mast Cell Activation Syndrome (MCAS) and its relationship with primary immunodeficiency and allergies is discussed. Dr. Maitland explains the roles of mast cells, their functions, and what triggers their inappropriate activation, which can lead to various symptoms like hives, anaphylaxis, and brain fog. During the talk, Dr. Maitland highlights the importance of recognizing symptoms in at least two organ systems to diagnose MCAS and discusses the limitations of current diagnostic testing. She also emphasizes the importance of treating underlying conditions like primary immunodeficiencies, that can exacerbate mast cell dysfunction. The presentation covers pharmacological management options such as antihistamines and mast cell stabilizers, as well as the need for collaborative care involving multiple specialties to tackle complex cases effectively. The Q&A session addressed practical concerns from patients regarding symptoms, testing, and treatment personalization for those with concurrent conditions like autoimmunity, connective tissue disorders, and autonomic dysfunctions like POTS.