Management of Postural Orthostatic Tachycardia Syndrome in the Absence of Randomized Controlled Trials.

The resource reviews the management of POTS in the absence of randomized controlled trial data, exploring both nonpharmacological and pharmacological interventions. It highlights treatments identified through various study types, including cross-sectional, cohort, and retrospective studies. Treatments are categorized into first-, second-, and third-line therapies based on the authors' clinical experience and existing data. The aim is to provide a structured approach to managing POTS despite the lack of extensive trial data.