Long-COVID syndrome-associated brain fog and chemofog: Luteolin to the rescue.

This article explores the connection between long-COVID syndrome, especially brain fog, and similar cognitive symptoms in conditions like chemofog, ME/CFS, and MCAS. It proposes that neuroinflammation, potentially driven by mast cell activation and subsequent microglial activation, may be a key underlying mechanism for brain fog. The authors suggest that luteolin, a natural flavonoid with anti-inflammatory properties, could help reduce these symptoms. Specifically, a phytosomal formulation of luteolin in olive pomace oil is mentioned as a potential therapeutic option, offering a strategy to mitigate neurological inflammation and improve cognitive function in affected patients.