Is there a relationship between hypocapnia and tachycardia in postural orthostatic tachycardia syndrome (POTS)? A systematic review.

This systematic review explores the potential relationship between hypocapnia (reduced carbon dioxide in the blood) and tachycardia (increased heart rate) in individuals with Postural Orthostatic Tachycardia Syndrome (POTS). The study aims to clarify if hypocapnia contributes causally to tachycardia when patients move from a supine to an upright position. The review synthesizes current evidence to help both patients and clinicians understand if managing carbon dioxide levels could potentially influence tachycardia management in POTS patients. However, the review highlights the need for further research to establish a definitive causal link and effective strategies for management.