Inflammatory Biomarkers in Postural Orthostatic Tachycardia Syndrome with Elevated G-Protein-Coupled Receptor Autoantibodies.

The study investigates the connection between inflammation and postural orthostatic tachycardia syndrome (POTS), specifically focusing on the role of elevated G-protein-coupled receptor autoantibodies. The authors suggest that POTS may have an autoimmune component. Previous research indicated that a significant percentage of POTS patients exhibited these autoantibodies, pointing towards immune system involvement in the disorder. The current study aims to explore inflammatory biomarkers in these patients, which could enhance understanding of POTS' underlying mechanisms and improve diagnostic criteria.