Hyperventilation in POTS with Jacquie Baker, PhD

Dr. Jacquie Baker discusses her research on hyperventilation in POTS, investigating claims that POTS might be primarily a respiratory disorder due to abnormal breathing patterns. By comparing POTS patients with healthy controls, it was found that hyperventilation in POTS is linked to reduced stroke volume and brain perfusion, rather than being a result of anxiety. This conclusion was supported by animal studies manipulating brainstem blood flow. Current research aims to determine the exact components of hyperventilation that exacerbate symptoms, exploring CO2 manipulation as a potential treatment. The study reassures patients that hyperventilation is a physiological response rather than a psychological issue.

Underlying Mechanisms Symptoms Testing Nonpharmacological Treatments
Published April 28, 2025
Hyperventilation in POTS with Jacquie Baker, PhD
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The POTScast

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