hEDS vs HSD: Controversies in Diagnosis with Alan Hakim, MD (Ep 110)

In this episode of the Bendy Bodies podcast, Dr. Linda Bluestein interviews Dr. Alan Hakim about the complexities of diagnosing hypermobile Ehlers-Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD). Dr. Hakim discusses the differences between hereditary and autoimmune connective tissue disorders, stressing the importance of joint instability over mere hypermobility. He critiques the Beighton Score's limitations and highlights the evolving criteria for diagnosing hEDS, underlining the role of comorbidities like POTS. Genetic testing is debated, with Dr. Hakim outlining when it's necessary and how to handle variants of uncertain significance. He emphasizes the potential for future studies to better define hEDS and provide genetic markers for diagnosis. Dr. Hakim advocates for maintaining physical activity and stresses the necessity of comprehensive patient evaluation while addressing barriers in the healthcare system.