Effect of lower body negative pressure on cardiac and cerebral function in postural orthostatic tachycardia syndrome: A pilot MRI assessment.
This study investigates the response of individuals with Postural Orthostatic Tachycardia Syndrome (POTS) to lower body negative pressure (LBNP), a technique that simulates the fluid shifts that occur upon standing. Using magnetic resonance imaging, the study examines changes in cardiac and cerebrovascular functions, such as biventricular volumes, stroke volume, cardiac output, and cerebral oxygen uptake, in POTS patients compared to healthy controls. The findings suggest that patients with POTS experience greater declines in these functions during LBNP, providing insights into the physiological alterations in POTS and potential diagnostic approaches.
Published March 16, 2024
