Drug excipients and label inconsistencies with Data Scientist Mike Brook

In a discussion featuring data scientist Mike Brook, a significant issue with drug labels listed in the DailyMed database was revealed. Patients with conditions like POTS, MCAS, and EDS are often sensitive to drug excipients (inactive ingredients), and they rely on resources like DailyMed to identify suitable medications. However, research has shown that there are inconsistencies in approximately 40% of drug labels on DailyMed, where inactive ingredient listings differ within the same drug's label. This is particularly concerning for sensitive patients as certain excipients, including common allergens like lactose and cornstarch, can cause reactions. The research, initially conducted on 100 drugs and later expanded to over a thousand using AI, indicates a systemic issue in drug labeling. Patients are advised to cross-check both lists of excipients on a label, contact drug manufacturers for clarification, and consider compounding pharmacies to tailor medications to their needs. The issue highlights challenges in medication management for sensitive patients but also suggests actionable steps to mitigate potential risks.