Dr. Dempsey on Infections: Mast Cell Matters with Dr. Tania Dempsey

In this episode, Dr. Tania Dempsey discusses how infections can be a trigger for Mast Cell Activation Syndrome (MCAS) and explores various vectors of transmission like insects and animals. She emphasizes the importance of testing for vector-borne infections in patients with MCAS and explains why antibody tests may not be reliable due to suppressed immune responses or abnormal antibody production. Instead, Dr. Dempsey recommends molecular tests, like PCR and FISH, to detect active infections with more accuracy. She also introduces SOT therapy, a promising treatment option that avoids heavy antibiotic use, especially useful for patients with heightened sensitivities. While infections often coexist with MCAS and treatment can be prolonged, early and accurate detection can significantly impact recovery and management of symptoms. Dr. Dempsey advises a balanced lifestyle approach to minimize exposures and stay proactive about health. The discussion includes personal anecdotes highlighting the challenges of mitigating tick and insect exposure while maintaining everyday life.