Dr. Blair P. Grubb, MD, Cardiovascular Medicine: Autonomic Dysfunction & Chronic Fatigue in EDS

Dr. Blair P. Grubb discusses autonomic dysfunction, focusing on its prevalence in Ehlers-Danlos Syndrome (EDS) and its connection to Postural Orthostatic Tachycardia Syndrome (POTS). The presentation outlines how autonomic dysfunction occurs due to inadequate blood pressure compensations upon standing, leading to symptoms like dizziness and fainting. Dr. Grubb highlights the diagnostic process using tilt table testing and the discovery of varied patterns of autonomic response. He emphasizes the complexity of autonomic disorders, noting heterogeneous presentations, and suggests a potential link with autoimmune issues. Dr. Grubb underscores the importance of physical reconditioning and pharmaco-therapies as part of management strategies for these conditions.