Dr. Anne Maitland - Mast Cell Activation Disorders

Dr. Anne Maitland discusses mast cell activation disorders, focusing on the complex role mast cells play in the immune system and how they can contribute to a range of symptoms and conditions. She explains that mast cells act as first responders to perceived dangers in the body, releasing various chemicals like histamines and tryptases in response to allergens or threats. However, inappropriate activation can lead to systemic issues, commonly seen in conditions like Mast Cell Activation Syndrome (MCAS), Ehlers-Danlos Syndrome (EDS), and Postural Orthostatic Tachycardia Syndrome (POTS). Maitland highlights the importance of thorough diagnosis and understanding, involving detailed assessment and specific tests to confirm overactive mast cells. She also emphasizes the role of both pharmacological treatments, such as antihistamines and mast cell stabilizers, and nonpharmacological approaches, like dietary adjustments, in managing symptoms effectively. Maitland discusses the need for a combined approach to treatment, as mast cell-related conditions often involve multiple organ systems, requiring input from various specialists.