Designing the Uplift compression device with Kishen Mitra and Sameer Kunte

In this episode, Kishen Mitra and Sameer Kunte discuss their research and development of the Uplift compression device aimed at helping POTS patients with their symptoms. They highlight the limitations of current compression therapies, including the discomfort and the lack of targeted design for POTS patients. The team has focused on engineering a device that can apply 40 mmHg of adjustable pressure, which is necessary for effective symptom relief, based on user feedback and clinical needs. Their design allows for dynamic pressure adjustment, making it more comfortable and practical for daily use. Mitra and Kunte also discuss the physiological benefits of compression in managing blood flow and preventing excessive heart rate increases characteristic of POTS when changing positions. They are working to bring this device to market following clinical validation to ensure it offers tangible benefits for POTS patients in real-world settings.