COVID-19 and Multisystem Inflammatory Syndrome, or is it Mast Cell Activation Syndrome?

This article discusses the overlapping symptoms between Multisystem Inflammatory Syndrome (MIS) seen in patients post-COVID-19 and Mast Cell Activation Syndrome (MCAS). Patients recovering from COVID-19 may experience symptoms such as malaise, myalgias, brain fog, and chest tightness, similar to those found in MCAS. The authors suggest evaluating for MCAS in individuals exhibiting symptoms of MIS, and they propose using specific treatments including a flavone luteolin formulation and the antihistamine rupatadine, which can help manage the pro-inflammatory and thrombogenic factors associated with these conditions.