Cerebral Blood Flow Findings with Marie-Claire Seeley, RN, PhD

In this episode, Dr. Marie-Claire Seeley discusses her research findings using SPECT imaging to assess cerebral blood flow in POTS patients with cognitive dysfunction. The study found significant abnormal blood flow in the brains of young POTS patients, even while supine, suggesting cerebral hypoperfusion. This was particularly notable in the prefrontal and sensory motor areas, which are associated with executive function and sensory integration. These findings support the idea that brain hypoperfusion is a real physiological issue in POTS, not merely psychological. Despite extensive cognitive impairment in the study population, the way POTS treatments impact brain perfusion remains unclear. Seeley emphasizes the importance of personalized management strategies, including exercise and investigating potential clotting disorders, given the heterogeneous nature of POTS. The research helps validate patient experiences and may assist in more accurate clinical assessments of POTS-related cognitive issues.