Ask the Expert featuring Ilene Ruhoy, MD, The Pentad Patient

Dr. Ilene Ruhoy discusses the concept of 'The Pentad Patient,' which often includes POTS, MCAS, GI dysfunctions, autoimmunity, and hypermobility type EDS. These conditions frequently co-occur in patients with Chiari malformation, cranial cervical instability, and tethered cord. Dr. Ruhoy outlines each condition, how they are diagnosed, and treatment approaches, noting the complexity due to overlapping symptoms and multi-system involvement. She highlights her approach to management, which includes both pharmacological and non-pharmacological strategies, emphasizing the importance of a personalized treatment plan. Dr. Ruhoy also touches on the expanded concept known as the 'Septad' patient, detailing the potential neurological symptoms associated with CCI in EDS patients and discussing treatment options for managing pain, headaches, and other symptoms. The session included a Q&A covering topics like finding knowledgeable neurosurgeons, the role of mast cells in connective tissue disorders, and the importance of patient-doctor communication in managing these complex conditions.