8. Demystifying Genetics with Paldeep Atwal, M.D.
In this podcast episode, Dr. Paldeep Atwal, a clinical and medical biochemical geneticist, explores the complex relationship between genetics and conditions like hypermobility disorders, including Ehlers-Danlos Syndrome (EDS), POTS, and MCAS. Dr. Atwal explains why joint hypermobility varies so widely among individuals and discusses the challenges in identifying genetic markers for hypermobile EDS. He highlights how epigenetic factors, such as nutrition and exercise, can impact gene expression, potentially offering a route for altering disease symptoms. Dr. Atwal also touches on the importance of genetic and pharmacogenetic testing in personalizing medical treatments. Throughout the conversation, Dr. Atwal emphasizes the evolving nature of genetic research and its implications for understanding complex genetic conditions and improving patient care.