190: Resiliency Radio with Dr. Jill: Manifestations of Mast Cell Activation (MCAS) in the Gut!

In this episode, Dr. Jill Carnahan interviews Dr. Leonard Weinstock about Mast Cell Activation Syndrome (MCAS) and its effects on the gut. Dr. Weinstock explains MCAS as a condition where mast cells become overactive, leading to a variety of systemic symptoms, including those affecting the gastrointestinal system. An increase in MCAS cases is noted, potentially due to environmental triggers and genetic predispositions. The discussion includes the challenges of diagnosing MCAS, which involves identifying symptoms across multiple body systems and utilizing specific lab tests. Dr. Weinstock discusses treatment options, including dietary changes and medications like antihistamines, flavonoids, and low-dose naltrexone. The conversation also covers MCAS's association with Ehlers-Danlos Syndrome and POTS, psychological symptoms linked to MCAS, and the need for more awareness and research on this condition. Dr. Weinstock is involved in creating a documentary to increase awareness and education about MCAS.